Transcription Factor
| Accessions: | Aef1 (DrosophilaTF 1.1), T057699_1.02 (CISBP 1.02) |
| Names: | Adult enhancer factor 1, AEF-1, AEF1_DROME, Aef1, T057699_1.02; |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, CISBP 1.02 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Uniprot: | P39413 |
| Notes: | experiment type:B1H, family:C2H2 ZF |
| Length: | 308 |
| Pfam Domains: | 180-194 Zinc-finger double domain 184-206 Zinc finger, C2H2 type 184-206 C2H2-type zinc finger 199-222 Zinc-finger double domain 212-234 Zinc finger, C2H2 type 212-234 C2H2-type zinc finger 212-232 Zinc-finger of C2H2 type 227-250 Zinc-finger double domain 240-262 Zinc finger, C2H2 type 240-262 C2H2-type zinc finger 255-278 Zinc-finger double domain 268-290 Zinc finger, C2H2 type 268-288 Zinc-finger of C2H2 type 268-290 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MMHIKSLPHAHAAATAMSSNCDIVIVAAQPQTTIANNNNNETVTQATHPAHMAAVQQQQQ 60 61 QQQQQQQQHHQQQQQQSSGPPSVPPPPTELPLPFQMHLSGISAEAHSAAQAAAMAAAQAA 120 121 AAQAAAAEQQQPPPPTSHLTHLTTHSPTTIHSEHYLANGHSEHPGEGNAAVGVGGAVREP 180 181 EKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPY 240 241 NCNFCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVK 300 301 IKTEEDEG |
| Interface Residues: | 194, 195, 196, 197, 198, 200, 201, 203, 204, 205, 207, 209, 212, 222, 223, 224, 225, 226, 228, 229, 233, 250, 251, 252, 253, 254, 255, 256, 257, 258, 261, 278, 279, 280, 281, 282, 283, 284, 285, 286, 301 |
| 3D-footprint Homologues: | 7w1m_H, 6jnm_A, 8cuc_F, 1f2i_J, 6u9q_A, 5ei9_F, 1g2f_F, 5k5i_A, 8ssq_A, 1tf6_A, 2gli_A, 1llm_D, 5k5l_F, 8ssu_A, 6ml4_A, 5v3j_F, 4x9j_A, 6blw_A, 5kkq_D, 7eyi_G, 6e94_A, 7ysf_A, 6wmi_A, 2lt7_A, 2i13_A, 6a57_A, 2jpa_A, 1ubd_C, 1yuj_A, 2kmk_A, 1tf3_A, 3uk3_C, 7n5w_A, 5yel_A, 7txc_E, 5kl3_A, 2drp_D, 5und_A, 8gn3_A, 1mey_C, 8h9h_G, 7y3m_I, 7y3l_A, 2wbs_A, 4m9v_C, 5yj3_D |
| Binding Motifs: | Aef1 CAACAA M4730_1.02 wGTwGTTG |
| Publications: | Ren B, Maniatis T. Regulation of Drosophila Adh promoter switching by an initiator-targeted repression mechanism. The EMBO journal 17:1076-86 (1998). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.