Transcription Factor
| Accessions: | P46604 (JASPAR 2024), T19303 (AthalianaCistrome v4_May2016) |
| Names: | HAT22_ARATH, HD-ZIP protein 22, Homeobox-leucine zipper protein HAT22, Homeodomain-leucine zipper protein HAT22, AT4G37790, HAT22, T19303; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | JASPAR 2024 1, AthalianaCistrome v4_May2016 2 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | ecotype:Col-0, experiment type: DAP-seq, family:Homeobox |
| Length: | 278 |
| Pfam Domains: | 125-179 Homeobox domain 181-224 Homeobox associated leucine zipper |
| Sequence: (in bold interface residues) | 1 MGLDDSCNTGLVLGLGLSPTPNNYNHAIKKSSSTVDHRFIRLDPSLTLSLSGESYKIKTG 60 61 AGAGDQICRQTSSHSGISSFSSGRVKREREISGGDGEEEAEETTERVVCSRVSDDHDDEE 120 121 GVSARKKLRLTKQQSALLEDNFKLHSTLNPKQKQALARQLNLRPRQVEVWFQNRRARTKL 180 181 KQTEVDCEFLKKCCETLTDENRRLQKELQDLKALKLSQPFYMHMPAATLTMCPSCERLGG 240 241 GGVGGDTTAVDEETAKGAFSIVTKPRFYNPFTNPSAAC |
| Interface Residues: | 70, 72, 74, 75, 110, 124, 125, 126, 127, 165, 166, 168, 169, 172, 173, 176, 177, 178, 179, 180, 202 |
| 3D-footprint Homologues: | 5h9f_G, 5zfz_A, 6m3d_C, 3lnq_A, 1nk2_P, 1zq3_P, 2lkx_A, 2ld5_A, 2r5y_A, 1puf_B, 1b72_A, 5zjt_E, 7psx_B, 6a8r_A, 3cmy_A, 2h1k_B, 1puf_A, 5flv_I, 5jlw_D, 1ig7_A, 7q3o_C, 1e3o_C, 1le8_A, 7xrc_C, 1au7_A, 4qtr_D, 1fjl_B, 4xrm_B, 3a01_E, 5hod_A, 3rkq_B, 1o4x_A, 1du0_A, 4xrs_G, 1jgg_B, 4cyc_A, 6es3_K, 3l1p_A, 2hdd_A, 2hos_A |
| Binding Motifs: | M0446 / MA1210.1 myyAATCATT MA1210.2 wwCAATAATTGww MA1210.3 CAATAATTG |
| Binding Sites: | MA1210.3.20 MA1210.2.1 MA1210.2.10 MA1210.2.11 MA1210.2.12 MA1210.2.13 MA1210.2.14 MA1210.2.15 MA1210.2.16 MA1210.2.17 MA1210.2.18 MA1210.2.19 MA1210.2.2 MA1210.2.20 MA1210.2.3 MA1210.2.4 MA1210.2.5 MA1210.2.6 MA1210.2.7 MA1210.2.8 MA1210.2.9 MA1210.3.10 / MA1210.3.11 / MA1210.3.16 / MA1210.3.5 / MA1210.3.6 MA1210.3.1 / MA1210.3.14 / MA1210.3.7 MA1210.3.13 / MA1210.3.2 / MA1210.3.8 MA1210.3.12 / MA1210.3.17 MA1210.3.15 / MA1210.3.18 MA1210.3.19 MA1210.3.3 MA1210.3.4 MA1210.3.9 |
| Publications: | Sessa G., Morelli G., Ruberti I. The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities. EMBO J. 12:3507-3517 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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