Transcription Factor

Accessions: CEBPB_full (HumanTF 1.0)
Names: CEBPB, CEBPB protein, Fragment, Q9BSC0_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9BSC0
Notes: Ensembl ID: ENSG00000172216; Full protein sequence; TF family: bZIP; Clone source: hORFeome
Length: 346
Pfam Domains: 270-323 Basic region leucine zipper
271-329 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MQRLVAWDPACLPLPPPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPA 60
61 GELGSIGDHERAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSD 120
121 LFSDDYGGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFE 180
181 PADCKRKEEAGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPAD 240
241 AKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQ 300
301 HKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASSGHC*
Interface Residues: 95, 277, 278, 281, 282, 284, 285, 288, 289, 292, 293
3D-footprint Homologues: 3pih_A, 2wt7_A, 6mg1_B, 1nwq_C, 5t01_B, 2wt7_B, 2c9l_Z, 2dgc_A
Binding Motifs: CEBPB_full rTTrCGCAAy
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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