Transcription Factor

Accessions: ECK120004493 (RegulonDB 7.5)
Names: CpxR, CpxR transcriptional dual regulator
Organisms: ECK12
Libraries: RegulonDB 7.5 1
1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Notes: specific transcriptional repressor activity; negative regulation of transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity; cytoplasm; two-component signal transduction system (phosphorelay); two-component response regulator activity; transcription activator activity; proteins/peptides/glycopeptides; detoxification; Transcription related; two component regulatory systems (external signal); repressor; activator; intracellular signal transduction; positive regulation of transcription, DNA-dependent
Length: 233
Pfam Domains: 4-112 Response regulator receiver domain
152-228 Transcriptional regulatory protein, C terminal
Sequence:
(in bold interface residues)
1 MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDSIDLLLLDVMMPKKNGI 60
61 DTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSHW 120
121 SEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGTEFTLLYLLAQHLGQVVSREH 180
181 LSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWFKTLRGRGYLMVSAS*
Interface Residues: 194, 195, 196, 198, 199, 200, 202, 203, 222
3D-footprint Homologues: 8jo2_H, 5x5l_H, 8hih_Q, 4kfc_B, 6lxn_A, 8hml_B, 4nhj_A, 7e1b_B, 5ed4_A, 2z33_A, 8b4b_W
Binding Motifs: CpxR GTAAArmwrygwaAr
Binding Sites: ECK120011212
ECK120011214
ECK120011216
ECK120011218
ECK120011322
ECK120012502
ECK120012504
ECK120012506
ECK120015590
ECK120016114
ECK120016116
ECK120016120
ECK120016123
ECK120016186
ECK120016233
ECK120016235
ECK120016237
ECK120016239
ECK120016241
ECK120016458
ECK120016460
ECK120016462
ECK120016464
ECK120016466
ECK120016468
ECK120016470
ECK120016801
ECK120016885
ECK120016892
ECK120016894
ECK120016896
ECK120017106
ECK120017107
ECK120017108
ECK120019268
ECK120029639
ECK120029870
ECK120029872
ECK120029874
ECK120029876
ECK120029878
ECK120029880
ECK120029882
ECK120029884
ECK120029886
ECK125110219
ECK125110221
ECK125110223
ECK125110225
ECK125110227
ECK125110229
ECK125110231
ECK125110233
ECK125110235
ECK125141167
ECK125141169
ECK125141171
ECK125141173
ECK125141175
ECK125141177
ECK125141179
ECK125141181
ECK125141183
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.