Transcription Factor

						

			
Accessions: 1je8_E (3D-footprint 20231221), 1zg5_E (3D-footprint 20231221)

			
Names: NARL_ECOLI, Nitrate/Nitrite Response Regulator Protein NARL
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0AF28
Length: 67
Pfam Domains:      5-60 Bacterial regulatory proteins, luxR family
     5-50 Sigma-70, region 4
     5-49 Sigma-70, region 4
     9-48 Winged helix-turn-helix DNA-binding
Sequence: 
(in bold interface residues)		   1 ERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVW   60
  61 VHQERIF
Interface Residues: 34, 35, 36, 37, 39, 40, 41, 42, 43, 48, 49, 51, 52, 53
3D-footprint Homologues: 7ve5_B, 4m6f_A, 5w43_B, 8dq1_C, 4wuh_B, 1je8_F, 1zlk_A
Binding Motifs: 1je8_EF TaCCnAnnnnTnGGtA
1zg5_E ThCCmC
1zg5_EF TACCCCtnnAGGGGTA
Binding Sites: 1zg5_G / 1zg5_H
			
Publications: Maris AE., Sawaya MR., Kaczor-Grzeskowiak M., Jarvis MR., Bearson SM., Kopka ML., Schroder I., Gunsalus RP., Dickerson RE. Dimerization allows DNA target site recognition by the NarL response regulator. Nat Struct Biol. 9(10):771-8 (2002). [Pubmed]


Maris AE., Kaczor-Grzeskowiak M., Ma Z., Kopka ML., Gunsalus RP., Dickerson RE. Primary and secondary modes of DNA recognition by the NarL two-component response regulator. Biochemistry. 44(44):14538-52 (2005). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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