Transcription Factor
| Accessions: | T016860_1.02 (CISBP 1.02), Q19917 (JASPAR 2024) |
| Names: | hlh-29, T016860_1.02;, Q19917_CAEEL |
| Organisms: | Caenorhabditis elegans |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q19917 |
| Notes: | experiment type:PBM, family:bHLH |
| Length: | 239 |
| Pfam Domains: | 24-67 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MPKVHQATFPKASVHSVPYNQTRKSVSERKRRDEINELLENLKTIVQNPSDSNEKISHET 60 61 ILFRVFERVSGVDLETKFNSTVDIPKAEGNTKEEKQKVKTKREQIRRSKQDICYTELGNF 120 121 VHKNRLGNTEQRNKLERVTVLQIILEYICQMPEQSEAIEKENSPMYQVYLEPTKCISPEQ 180 181 SVASPSPFLLSNTLAFFNQVAQLHFIAKLQAMLPPTPVQTPEAHMKEQTNEEEDIDIIG |
| Interface Residues: | 22, 28, 31, 32, 37, 40, 41 |
| 3D-footprint Homologues: | 6rwn_I, 5eyo_A, 8osl_P, 4h10_A |
| Binding Motifs: | PL0008.1 cwrhyACGCrTGkyhwa M0226_1.02 mCAyGCGT UN0707.1 ACGCrTGk |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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