Transcription Factor

Accessions: CEBPE (HT-SELEX2 May2017)
Names: CEBPE, ENSG00000092067
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 143
Pfam Domains: 66-118 Basic region leucine zipper
67-124 bZIP transcription factor
Sequence:
(in bold interface residues)
1 NPLQYQVAHCGQTAMHLPPTLAAPGQPLRVLKAPLATAAPPCSPLLKAPSPAGPLHKGKK 60
61 AVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELD 120
121 TLRNLFRQIPEAANLIKGVGGCS
Interface Residues: 73, 76, 77, 79, 80, 83, 84
3D-footprint Homologues: 1nwq_C, 6mg1_B, 2c9l_Z, 2dgc_A, 5t01_B
Binding Motifs: CEBPE_2 brTTGCGyAAyv
CEBPE_methyl_1 yrTTGCGyAAyv
Related annotations: PaperBLAST

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