Transcription Factor
| Accessions: | F1JVV8 (JASPAR 2024) |
| Names: | F1JVV8_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | F1JVV8 |
| Length: | 526 |
| Pfam Domains: | 354-436 Ets-domain |
| Sequence: (in bold interface residues) | 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSLLAYNTTSHTDQSSRLSVKEDPSYDSVR 300 301 RGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQF 360 361 LLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKN 420 421 IMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPS 480 481 SMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY |
| Interface Residues: | 352, 407, 408, 410, 411, 412, 414, 415, 429 |
| 3D-footprint Homologues: | 3zp5_A, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B |
| Binding Motifs: | MA0149.1 GGAAGGAAGGAAGGAAGG |
| Binding Sites: | MA0149.1.1 / MA0149.1.10 / MA0149.1.11 / MA0149.1.14 / MA0149.1.18 / MA0149.1.2 / MA0149.1.5 / MA0149.1.7 MA0149.1.12 / MA0149.1.20 / MA0149.1.6 / MA0149.1.9 MA0149.1.13 MA0149.1.15 MA0149.1.16 MA0149.1.17 MA0149.1.19 MA0149.1.3 MA0149.1.4 MA0149.1.8 |
| Publications: | Guillon N, Tirode F, Boeva V, Zynovyev A, Barillot E, Delattre O. The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function. PloS one 4:e4932 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.