Transcription Factor

						

			
Accessions: Q7RTU3 (JASPAR 2024)

			
Names: bHLHb7, bHLHe20, Class B basic helix-loop-helix protein 7, Class E basic helix-loop-helix protein 20, OLIG3_HUMAN, Oligo3, Oligodendrocyte transcription factor 3
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q7RTU3
Length: 272
Pfam Domains:    86-137 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAG   60
  61 AKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRK  120
 121 LSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHP  180
 181 VHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCP  240
 241 CTICQMPPPPHLSALSTANMARLSAESKDLLK
Interface Residues: 85, 89, 91, 92, 95, 96
3D-footprint Homologues: 2ypa_A, 2ql2_D, 2ypa_B
Binding Motifs: MA0827.1 AmCATATGby
			
Publications: Küspert M, Hammer A, Bösl MR, Wegner M. Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer. Nucleic Acids Res 39:1280-93 (2011). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.