Transcription Factor

Accessions: CEBPB (SMILE-seq 1.0)
Names: CEBPB, CEBPB protein, Fragment, Q9BSC0_HUMAN
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: Q9BSC0
Notes: TF family: bZIP
Length: 344
Pfam Domains: 270-323 Basic region leucine zipper
271-329 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MQRLVAWDPACLPLPPPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPA 60
61 GELGSIGDHERAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSD 120
121 LFSDDYGGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFE 180
181 PADCKRKEEAGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPAD 240
241 AKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQ 300
301 HKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASSGH
Interface Residues: 95, 277, 278, 281, 282, 284, 285, 288, 289, 292, 293
3D-footprint Homologues: 3pih_A, 2wt7_A, 6mg1_B, 1nwq_C, 2wt7_B, 2c9l_Z, 2dgc_A, 5t01_B
Binding Motifs: CEBPB krTTrCGyAAy
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.