Transcription Factor

						

			
Accessions: T134216_1.02 (CISBP 1.02)

			
Names: Hnf4, T134216_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:B1H, family:Nuclear receptor
Length: 708
Pfam Domains:   145-213 Zinc finger, C4 type (two domains)
  265-458 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 MYASMLPSLLNMKTENLTSSSYDDAFLLEENLLHIMESESHIMHADALASAYPAASQPHS   60
  61 PIGLALSPNGGGLGLSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNL  120
 121 SGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQY  180
 181 TCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLS  240
 241 VISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAF  300
 301 NELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISR  360
 361 IGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYI  420
 421 SDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNP  480
 481 LPLSPPNQSNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANS  540
 541 ADDSFRAYAASTAAAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQES  600
 601 SYLDMPVKHYNGSRSGPLPTQHSPQRMHPYQRAVASPVEVSSGGGGLGLRNPADITLNEY  660
 661 NRSEGSSAEELLRRTPLKIRAPEMLTAPAGYGTEPCRMTLKQEPETGY
Interface Residues: 129, 154, 155, 157, 158, 164, 165, 167, 168, 171, 172, 196, 218, 220, 222, 225, 227, 229
3D-footprint Homologues: 7y3m_I, 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 2han_A, 1hcq_E, 8cef_H, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 4iqr_B, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A
Binding Motifs: M5030_1.02 wkktwssyGGGGTCA
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.