Transcription Factor

Accessions: UP00572A (UniPROBE 20160601)
Names: ANAC092, ARABIDOPSIS NAC DOMAIN CONTAINING PROTEIN 2, ARABIDOPSIS NAC DOMAIN CONTAINING PROTEIN 6, Arabidopsis NAC domain containing protein 92, ATNAC2, MIJ24_11, MIJ24.11, NAC-domain transcription factor, NAC6, ORE1, ORESARA 1
Organisms: Arabidopsis thaliana
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: NAC-domain transcription factor: Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[ACG][CA]GT[AG](5-6n)[CT]AC[AG]-3' (PubMed:23340744). Promotes lateral root development (PubMed:16359384). Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with sal
Length: 176
Pfam Domains: 20-146 No apical meristem (NAM) protein
Sequence:
(in bold interface residues)
1 MDYEASRIVEMVEDEEHIDLPPGFRFHPTDEELITHYLKPKVFNTFFSATAIGEVDLNKI 60
61 EPWDLPWKAKMGEKEWYFFCVRDRKYPTGLRTNRATEAGYWKATGKDKEIFKGKSLVGMK 120
121 KTLVFYKGRAPKGVKTNWVMHEYRLEGKYCIENLPQTAKNEWVICRVFQKRADGTK
Interface Residues: 86, 91, 93, 102, 104, 106, 126, 130, 131, 132, 135
3D-footprint Homologues: 7xp3_B, 3swp_A
Binding Motifs: UP00572A_1 myACACGCAAycd
UP00572A_2 htACACGCAAcck
UP00572A_3 cwACACGCAACC
UP00572A_4 wtACACGCAACck
Binding Sites: CACGCCAC
TTACGCAA
ACACGCAA
ACACGCCA
ACACGCTA
ACACGGCA
ACACGTAA
ACACGTCA
ACACGTTA
ACGCAACC
ACGCAATC
ATACGCAA
ATTGCGTA
ATTGCGTG
CACGCAAA
CACGCAAC
GCACGCAA
GTACGCAA
GTTGCGTA
TCACGCAA
Publications: Lindemose S, Jensen MK, Van de Velde J, O'Shea C, Heyndrickx KS, Workman CT, Vandepoele K, Skriver K, De Masi F. A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana. Nucleic Acids Res 42:7681-93 (2014). [Pubmed]
Related annotations: PaperBLAST

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