Transcription Factor
| Accessions: | P31362 (JASPAR 2024) |
| Names: | Epoc-1, Oct-11, Octamer-binding protein 11, Octamer-binding transcription factor 11, OTF-11, PO2F3_MOUSE, POU domain, class 2, transcription factor 3 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P31362 |
| Length: | 431 |
| Pfam Domains: | 177-250 Pou domain - N-terminal to homeobox domain 275-331 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MVNLEPMHTEIKMSGDVADSTDTRSTFGQVEPGNDRNGLDFNRQIKTEDLGDSLQQTLSH 60 61 RPCHLSQGPTMMPGNQMSGDMASLHPLQQLVLVPGHLQSVSQFLLSQTPPGQQGLQPNLL 120 121 SFPQQQSTLLLPQTGPGLRSQAVGRPGLSGSSLEPHLDAPQHLPGPKHLPGPGGNDEPTD 180 181 LEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKP 240 241 LLEKWLNDPESSPSDPSASTPSSYPTLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPS 300 301 SEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPVKPPIYNSRLVSPSGSLGPLS 360 361 VPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAMNSSSSSSFNSSGS 420 421 WYRWNHPTYLH |
| Interface Residues: | 202, 218, 219, 220, 221, 223, 224, 230, 234, 275, 276, 277, 278, 316, 317, 319, 320, 323, 324, 327, 328, 331 |
| 3D-footprint Homologues: | 3d1n_M, 3l1p_A, 7u0g_M, 8g87_X, 1e3o_C, 2xsd_C, 1au7_A, 1o4x_A, 7xrc_C, 5zjt_E, 4cyc_A, 1fjl_B, 6a8r_A, 5jlw_D, 1puf_A, 1ig7_A, 3cmy_A, 2h1k_B, 5zfz_A, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 7q3o_C, 2ld5_A, 6es3_K, 1puf_B, 7psx_B, 2hdd_A, 5hod_A, 3a01_E, 1b72_A, 4xrs_G, 3rkq_B, 2r5y_A, 1le8_A, 5flv_I, 1k61_B, 4qtr_D, 2d5v_B, 1mnm_C, 1du0_A |
| Binding Motifs: | MA0627.1 / PH0145.1 ttkTATGCWAATkara |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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