Transcription Factor
| Accessions: | Q9R1R0 (JASPAR 2024) |
| Names: | LHX6_MOUSE, LIM homeobox protein 6, LIM/homeobox protein Lhx6, LIM/homeobox protein Lhx6.1 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9R1R0 |
| Length: | 363 |
| Pfam Domains: | 70-127 LIM domain 131-185 LIM domain 220-276 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGRASPCTPSTPSVCSPPSAAS 60 61 SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCK 120 121 MDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVL 180 181 CRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQ 240 241 DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPTRLPSALSDD 300 301 IHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADLDGPLSSRGEKVIL 360 361 FQY |
| Interface Residues: | 220, 221, 222, 223, 261, 262, 264, 265, 268, 269, 272, 273, 276 |
| 3D-footprint Homologues: | 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 3d1n_M, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 4cyc_A, 7psx_B, 5hod_A, 3l1p_A, 3a01_E, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 2xsd_C, 1e3o_C, 7xrc_C, 1o4x_A, 1du0_A, 4qtr_D, 1le8_B |
| Binding Motifs: | PH0096.1 swrcryTAATTArkkyw PH0097.1 wmcrCTAATTAGcggwk |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.