Transcription Factor

Accessions: P13297 (JASPAR 2024)
Names: Homeobox protein Hox-7, Homeobox protein MSX-1, Hox-7.1, Msh homeobox 1-like protein, MSX1_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P13297
Length: 303
Pfam Domains: 173-229 Homeobox domain
Sequence:
(in bold interface residues)
1 MAPAAAMTSLPLGVKVEDSAFAKPAGGGVGQAPGAAAATATAMGTDEEGAKPKVPASLLP 60
61 FSVEALMADHRKPGAKESVLVASEGAQAAGGSVQHLGTRPGSLGAPDAPSSPRPLGHFSV 120
121 GGLLKLPEDALVKAESPEKLDRTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFT 180
181 TAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKM 240
241 AAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYSASGPFQRAALPVAPVGLYTAHVGYSMY 300
301 HLT
Interface Residues: 171, 173, 174, 175, 176, 214, 215, 217, 218, 221, 222, 225, 226, 229
3D-footprint Homologues: 6fqp_B, 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 6es3_K, 7q3o_C, 2ld5_A, 2hdd_A, 7psx_B, 5jlw_D, 3rkq_B, 2r5y_A, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 5zjt_E, 4j19_B, 3a01_E, 5hod_A, 3lnq_A, 1jgg_B, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 1mnm_C, 1puf_B, 1k61_B, 3l1p_A, 1o4x_A, 1le8_B, 1du0_A, 8g87_X, 4qtr_D
Binding Motifs: PH0106.1 krmwayTAATTAatwm
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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