Transcription Factor

Accessions: 5e01_B (3D-footprint 20231221)
Names: Uncharacterized HTH-type transcriptional regulator HI_0186, Y186_HAEIN
Organisms: Haemophilus influenzae, strain ATCC 51907 / DSM 11121 / KW20 / Rd
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P44558
Length: 127
Pfam Domains: 4-69 MerR HTH family regulatory protein
5-42 MerR family regulatory protein
48-108 MerR, DNA binding
Sequence:
(in bold interface residues)
1 AMTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTG 60
61 MSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKA 120
121 LGSVKAV
Interface Residues: 18, 21, 22, 25, 26, 39, 40
3D-footprint Homologues: 7ckq_G, 5c8e_C, 6ldi_G, 2vz4_A, 7tea_B, 5d8c_A, 6xh7_H, 2zhg_A, 7tec_A, 5i44_I, 1r8d_B, 6xl5_H, 4r4e_B, 1r8e_A, 6jgx_B
Binding Motifs: 5e01_AB AGAGnnnnCTCT
Binding Sites: 5e01_C / 5e01_D
Publications: Couñago RM, Chen NH, Chang CW, Djoko KY, McEwan AG, Kobe B. Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region 44:6981-93 (Nucleic). [Pubmed]
Related annotations: PaperBLAST

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