Transcription Factor

Accessions: P56672 (JASPAR 2024)
Names: OTP_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P56672
Length: 409
Pfam Domains: 110-166 Homeobox domain
Sequence:
(in bold interface residues)
1 MLNNLGANVLGPKDCDLPKAALTALHAGVNSFGQLPVGPNLADLGGGAGGGGSSGGVPVG 60
61 GGVARLHISGGLCDNSNALNGGNGSSGNGNGNNNNGNGNNNNSMQQQDQKRHRTRFTPAQ 120
121 LNELERCFSKTHYPDIFMREEIAMRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGAL 180
181 LPSHGLPPFGANITNIAMGDGLCGTGMFGGDRWSVGVNPMTAGFGQLNQSSPLSSSLNSG 240
241 LNSGINMGSALGAGSYQHYGLNALGDSMMYQHSVGGVSCGPSGSPSATTPPNMNSCSSVT 300
301 PPPLSAQPNSSQNELNGEPMPLHQQQQQQTHQHQQQQTHQHHPMAPPTPTQQQQQLPQSM 360
361 QSPSDGANDTLHSIAALRRRASELNAIPSYLQMAPHNYEHYNSNSNSVY
Interface Residues: 48, 64, 65, 66, 67, 69, 70, 79, 83, 109, 110, 111, 112, 113, 115, 151, 152, 154, 155, 158, 159, 162, 163, 166
3D-footprint Homologues: 3l1p_A, 3a01_E, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 5zfz_A, 1ig7_A, 4j19_B, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 6es3_K, 7q3o_C, 2ld5_A, 5hod_A, 2hdd_A, 7psx_B, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 5zjt_E, 1e3o_C, 1le8_A, 2xsd_C, 7xrc_C, 6wig_A, 8g87_X, 4qtr_D, 1o4x_A, 1du0_A
Binding Motifs: MA0236.1 yTAATTA
Binding Sites: MA0236.1.19
MA0236.1.18
MA0236.1.10
MA0236.1.17
MA0236.1.12
MA0236.1.1
MA0236.1.11
MA0236.1.13
MA0236.1.14
MA0236.1.15
MA0236.1.16
MA0236.1.2
MA0236.1.20
MA0236.1.3
MA0236.1.4
MA0236.1.5
MA0236.1.6
MA0236.1.7
MA0236.1.8
MA0236.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.