Transcription Factor
Accessions: | Q07120 (JASPAR 2024) |
Names: | GFI1_RAT, Growth factor independent protein 1, Zinc finger protein Gfi-1 |
Organisms: | Rattus norvegicus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 423 |
Pfam Domains: | 256-279 Zinc finger, C2H2 type 256-279 C2H2-type zinc finger 271-296 Zinc-finger double domain 285-307 Zinc finger, C2H2 type 285-307 C2H2-type zinc finger 286-309 C2H2-type zinc finger 299-324 Zinc-finger double domain 313-335 Zinc finger, C2H2 type 313-332 Zinc-finger of C2H2 type 313-335 C2H2-type zinc finger 315-331 C2H2-type zinc finger 328-351 Zinc-finger double domain 341-359 C2H2-type zinc finger 341-363 Zinc finger, C2H2 type 341-350 C2H2-type zinc finger 356-379 Zinc-finger double domain 368-391 C2H2-type zinc finger 369-391 C2H2-type zinc finger 369-391 Zinc finger, C2H2 type 383-406 Zinc-finger double domain 397-420 C2H2-type zinc finger 398-420 Zinc finger, C2H2 type 399-420 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MPRSFLVKSKKAHSYHQPRSPGPDYSLRLETVPVPGRADGGAVSAGESKMEPRERLSPES 60 61 QLTEAPDRASASPNSCEGSVCDPSSEFEDYWRPPSPSVSPASEKSLCRSLDEAQPYTLPF 120 121 KPYAWSGLAGSDLRHLVQSYRQCSALERSAGLSLFCERGAESGRPAARYGSEQAAGGAGA 180 181 GQPGSCGAASGATSAGGLGLYGDFAPAAAGLFERPSTAAGRLYQDRGHELHADKSVGVKV 240 241 ESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSL 300 301 EQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHT 360 361 FIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQH 420 421 GLK |
Interface Residues: | 214, 216, 217, 220, 242, 243, 244, 267, 269, 270, 273, 277, 295, 296, 297, 298, 299, 302, 303, 306, 313, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 336, 351, 352, 353, 354, 355, 357, 358, 361, 379, 380, 381, 382, 383, 385, 386, 407, 408, 409, 410, 411, 412, 413, 414, 418 |
3D-footprint Homologues: | 5v3j_F, 6wmi_A, 5und_A, 8ssq_A, 1tf6_A, 5kkq_D, 8ssu_A, 8gh6_A, 7y3m_I, 6jnm_A, 5k5i_A, 7w1m_H, 4m9v_C, 6e94_A, 7ysf_A, 2i13_A, 5yel_A, 2kmk_A, 7n5w_A, 5ei9_F, 8gn3_A, 2drp_D, 2gli_A, 6ml4_A, 8h9h_G, 7eyi_G, 2lt7_A, 6a57_A, 2jpa_A, 1ubd_C, 3uk3_C, 1tf3_A, 1mey_C, 7txc_E, 5kl3_A, 1f2i_J, 1g2f_F, 5k5l_F, 4x9j_A, 6blw_A, 2wbs_A, 6u9q_A, 8cuc_F, 7y3l_A, 1llm_D, 5yj3_D |
Binding Motifs: | MA0038.1 ymAATCacwg |
Binding Sites: | MA0038.1.1 MA0038.1.10 MA0038.1.11 MA0038.1.12 MA0038.1.13 MA0038.1.14 MA0038.1.15 MA0038.1.16 MA0038.1.17 MA0038.1.18 MA0038.1.19 MA0038.1.2 MA0038.1.20 MA0038.1.3 MA0038.1.4 MA0038.1.5 MA0038.1.6 MA0038.1.7 MA0038.1.8 MA0038.1.9 |
Publications: | Zweidler-McKay P. A., Grimes H. L., Flubacher M. M., Tsichlis P. N. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Mol. Cell. Biol. 16:4024-4034 (1996). [Pubmed] |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.