Transcription Factor

Accessions: T015153_1.02 (CISBP 1.02)
Names: Hey2, T015153_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 339
Pfam Domains: 53-104 Helix-loop-helix DNA-binding domain
123-163 Hairy Orange
Sequence:
(in bold interface residues)
1 MKRPCEETTSESDLDETIDVGSENNYPGHATSSVMRSNSPTTTSQIMARKKRRGIIEKRR 60
61 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALATD 120
121 FMSIGFRECLTEVARYLSSVEGLDPSDPLRVRLVSHLSTCASQREAAVMTSSMAHHHHPL 180
181 HPHHWAAAFHHLPTALLQPNGLHTSESTPCRLSTSSEVPSAHGSALLTATFAHADSALRM 240
241 PSGGTVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPSNAAAAAAVA 300
301 AATAISPPLSVSAASSPQQTSTGTNNKPYQPWGTEVGAF
Interface Residues: 50, 52, 53, 54, 56, 57, 60, 61, 87, 89
3D-footprint Homologues: 7z5k_B, 1an4_A, 6g1l_A, 5eyo_A, 1am9_A, 5sy7_B, 4h10_B, 7f2f_B, 8osl_O, 7ssa_L, 2ql2_D, 7xi3_A, 4h10_A, 5nj8_D, 2ypa_A, 8osl_P, 7d8t_A, 5gnj_I, 5v0l_A, 4zpk_A, 1a0a_B, 5nj8_C, 5v0l_B
Binding Motifs: M0183_1.02 gaCACGTGy
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.