Transcription Factor
| Accessions: | CDX1_HUMAN (HOCOMOCO 10), P47902 (JASPAR 2024) |
| Names: | Caudal-type homeobox protein 1, CDX1_HUMAN, Homeobox protein CDX-1 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P47902 |
| Length: | 265 |
| Pfam Domains: | 13-146 Caudal like protein activation region 156-211 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MYVGYVLDKDSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTA 60 61 WGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPG 120 121 TPSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYIT 180 181 IRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPPQPPMAHDITATPAGPSL 240 241 GGLCPSNTSLLATSSPMPVKEEFLP |
| Interface Residues: | 155, 156, 157, 158, 196, 197, 199, 200, 203, 204, 207, 208, 211 |
| 3D-footprint Homologues: | 1puf_A, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 1jgg_B, 7q3o_C, 6es3_K, 2ld5_A, 3cmy_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 1fjl_B, 5zfz_A, 4cyc_A, 6m3d_C, 5flv_I, 1ig7_A, 5zjt_E, 3a01_E, 2h1k_B, 7psx_B, 6a8r_A, 1e3o_C, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 4xrm_B, 1mnm_C, 1puf_B, 1k61_B, 3d1n_M, 1b72_A, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D, 1le8_B, 1du0_A, 5hod_A |
| Binding Motifs: | MA0878.1 gymATAAAa MA0878.2 gGYmATAAAac CDX1_HUMAN.H10MO.C|M01046 aTTTAtGk MA0878.3 GGymATAAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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