Transcription Factor
Accessions: | T004905_1.02 (CISBP 1.02), Q6VUP9 (JASPAR 2024) |
Names: | T004905_1.02;, Tcfap2e, Activating enhancer-binding protein 2-epsilon, AP2-epsilon, AP2E_MOUSE, Transcription factor AP-2-epsilon |
Organisms: | Mus musculus |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:AP-2 |
Length: | 442 |
Pfam Domains: | 214-419 Transcription factor AP-2 |
Sequence: (in bold interface residues) | 1 MLVHTYSAMERPDGLGAAAGGTRLSSLPQAAYGPAPPLCHTPAASATADYHPPYFPPPYP 60 61 QAPLPYGQGPDATAAFPHLAADPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPP 120 121 ARALGLDPRRDYAAAVPRLLHSLADGAHGLADAPLGLPGLAEPPGLEELQAIDDPGMSLL 180 181 DQSVIKKVPIPSKAGSLSTLALSKDSLVGGISNPSEVFCSVPGRLSLLSSTSKYKVTVGE 240 241 VQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLV 300 301 EGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMA 360 361 QDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLEKMF 420 421 LSGAGGGHGESKASEKDTKHRK |
Interface Residues: | 229, 263, 264 |
3D-footprint Homologues: | 8j0k_B |
Binding Motifs: | PB0088.1 wwhSCCysrGGSraw PB0192.1 wackkrAAAaAAwa M0085_1.02 tyGCCysmGG |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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