Transcription Factor

Accessions: 1a0a_A (3D-footprint 20231221), 1a0a_B (3D-footprint 20231221)
Names: PHO4_YEAST, PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P07270
Length: 63
Pfam Domains: 2-58 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MKRESHKHAEQARRNRLAVALHELASLIPAEWKQQNVSAAPSKATTVEAACRYIRHLQQN 60
61 GST
Interface Residues: 2, 3, 5, 6, 7, 9, 10, 13, 14, 41, 43
3D-footprint Homologues: 4zpr_B, 1a0a_B, 1an4_A, 5eyo_A, 7xi3_A, 5sy7_B, 4zpk_A, 7d8t_A, 5i50_B, 8osl_O, 5v0l_A, 4zpk_B, 7f2f_B, 4h10_A, 7ssa_L, 5nj8_D, 4h10_B, 6g1l_A, 8osl_P, 5nj8_C, 5v0l_B
Binding Motifs: 1a0a_AB CaCGTGG
1a0a_B cgTGG
Binding Sites: 1a0a_C
1a0a_D
Publications: Shimizu T, Toumoto A, Ihara K, Shimizu M, Kyogoku Y, Ogawa N, Oshima Y, Hakoshima T. Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition. The EMBO journal 16:4689-97 (1997). [Pubmed]
Related annotations: PaperBLAST

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