Transcription Factor

						

			
Accessions: NRF1_HUMAN (HOCOMOCO 10), Q16656 (JASPAR 2024)

			
Names: Alpha palindromic-binding protein, Alpha-pal, NRF-1, NRF1_HUMAN, Nuclear respiratory factor 1
Organisms: Homo sapiens
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 503
Pfam Domains:    75-285 NLS-binding and DNA-binding and dimerisation domains of Nrf1
  450-490 Nrf1 activator activation site binding domain
Sequence: MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILN
STAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLD
EYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQE
VNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPW
ANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHL
VPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNW
ATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAE
ATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPV
TTRISDSAVTMDGQAVEVVTLEQ
Binding Motifs: NRF1_HUMAN.H10MO.A|M01401 syGCGCmTGCGCrgkgss
MA0506.1 GCGCmTGCGCr
Binding Sites: MA0506.1.1
MA0506.1.10
MA0506.1.11
MA0506.1.12
MA0506.1.13
MA0506.1.14
MA0506.1.15
MA0506.1.16
MA0506.1.17
MA0506.1.18
MA0506.1.19
MA0506.1.2
MA0506.1.20
MA0506.1.3
MA0506.1.4
MA0506.1.5
MA0506.1.6
MA0506.1.7
MA0506.1.8
MA0506.1.9
			
Publications: Morrish F, Giedt C, Hockenbery D. c-MYC apoptotic function is mediated by NRF-1 target genes. Genes & development 17:240-55 (2003). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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