Transcription Factor

Accessions: Ubx (DrosophilaTF 1.1), P83949 (JASPAR 2024)
Names: UBX_DROME
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1, JASPAR 2024 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 389
Pfam Domains: 296-352 Homeobox domain
Sequence:
(in bold interface residues)
1 MNSYFEQASGFYGHPHQATGMAMGSGGHHDQTASAAAAAYRGFPLSLGMSPYANHHLQRT 60
61 TQDSPYDASITAACNKIYGDGAGAYKQDCLNIKADAVNGYKDIWNTGGSNGGGGGGGGGG 120
121 GGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRG 180
181 GSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTFY 240
241 PWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQ 300
301 TYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKEL 360
361 NEQEKQAQAQKAAAAAAAAAAVQGGHLDQ
Interface Residues: 295, 296, 297, 298, 299, 300, 322, 326, 329, 330, 333, 337, 338, 340, 341, 344, 345, 348, 349, 352
3D-footprint Homologues: 4j19_B, 1puf_A, 3a01_E, 1ig7_A, 2h1k_B, 6a8r_A, 1fjl_B, 3cmy_A, 5zfz_A, 1zq3_P, 6m3d_C, 3d1n_M, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 2ld5_A, 5flv_I, 5zjt_E, 7psx_B, 5hod_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 6es3_K, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 2wt7_A, 2xsd_C, 1e3o_C, 1le8_A, 1au7_A, 7xrc_C, 1o4x_A, 1du0_A, 4qtr_D
Binding Motifs: MA0094.2 yTTAATKR
Ubx kdrgrstTAATkGsytygk
MA0094.1 TAAT
MA0094.3 TTAATKR
Binding Sites: Ubx_1
Ubx_2
Ubx_5
Ubx_10
Ubx_11
Ubx_12
Ubx_16
Ubx_20
Ubx_24
Ubx_27
Ubx_28
Ubx_31
Ubx_33
Ubx_36
Ubx_39
Ubx_40
Ubx_44
Ubx_49
Ubx_56
Ubx_58
Ubx_65
Ubx_70
Ubx_72
Ubx_75
Ubx_81
Ubx_86
Ubx_88
Ubx_13
Ubx_14
Ubx_15
Ubx_17
Ubx_18
Ubx_19
Ubx_21
Ubx_22
Ubx_23
Ubx_25
Ubx_26
Ubx_29
Ubx_3
Ubx_30
Ubx_32
Ubx_34
Ubx_35
Ubx_37
Ubx_38
Ubx_4
Ubx_41
Ubx_42
Ubx_43
Ubx_45
Ubx_46
Ubx_47
Ubx_48
Ubx_50
Ubx_51
Ubx_52
Ubx_53
Ubx_54
Ubx_55
Ubx_57
Ubx_59
Ubx_6
Ubx_60
Ubx_61
Ubx_62 / Ubx_63
Ubx_64
Ubx_66
Ubx_67
Ubx_68
Ubx_69 / Ubx_71
Ubx_7
Ubx_73
Ubx_74
Ubx_76
Ubx_77
Ubx_78
Ubx_79
Ubx_8
Ubx_80
Ubx_82
Ubx_83
Ubx_84
Ubx_85
Ubx_87
Ubx_9
MA0094.1.1
MA0094.1.10 / MA0094.1.8
MA0094.1.11
MA0094.1.12
MA0094.1.13
MA0094.1.14
MA0094.1.15 / MA0094.1.5
MA0094.1.16
MA0094.1.17
MA0094.1.18
MA0094.1.19
MA0094.1.2
MA0094.1.20
MA0094.1.3
MA0094.1.4
MA0094.1.6
MA0094.1.7
MA0094.1.9
MA0094.2.1
MA0094.2.10
MA0094.2.11
MA0094.2.12 / MA0094.2.17
MA0094.2.13
MA0094.2.14
MA0094.2.15
MA0094.2.16
MA0094.2.18
MA0094.2.19
MA0094.2.2
MA0094.2.20
MA0094.2.3 / MA0094.2.4
MA0094.2.5
MA0094.2.6
MA0094.2.7
MA0094.2.8
MA0094.2.9
MA0094.3.13 / MA0094.3.20 / MA0094.3.7
MA0094.3.1
MA0094.3.10
MA0094.3.11 / MA0094.3.14
MA0094.3.12 / MA0094.3.16 / MA0094.3.17
MA0094.3.15
MA0094.3.18
MA0094.3.19
MA0094.3.2
MA0094.3.3 / MA0094.3.4
MA0094.3.5 / MA0094.3.8
MA0094.3.6
MA0094.3.9
Publications: Ekker S. C., Young K. E., von Kessler D. P., Beachy P. A. Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. EMBO J. 10:1179-1186 (1991). [Pubmed]

Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.