Transcription Factor
Accessions: | T061540_1.02 (CISBP 1.02), P39943 (JASPAR 2024) |
Names: | MIG3, T061540_1.02;, MIG3_YEAST, Multicopy inhibitor of growth protein 3, Transcription corepressor MIG3 |
Organisms: | Saccharomyces cerevisiae |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:C2H2 ZF |
Length: | 394 |
Pfam Domains: | 33-58 Zinc-finger double domain 45-69 Zinc finger, C2H2 type 45-69 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MNYLRDRFPPDNDQRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSD 60 61 ELKRHLRTHTKGVQRRRIKSKGSRKTVVNTATAAPTTFNENTGVSLTGIGQSKVPPILIS 120 121 VAQNCDDVNIRNTGNNNGIVETQAPAILVPVINIPNDPHPIPSSLSTTSITSIASVYPST 180 181 SPFQYLKSGFPEDPASTPYVHSSGSSLALGELSSNSSIFSKSRRNLAAMSGPDSLSSSKN 240 241 QSSASLLSQTSHPSKSFSRPPTDLSPLRRIMPSVNTGDMEISRTVSVSSSSSSLTSVTYD 300 301 DTAAKDMGMGIFFDRPPVTQKACRSNHKYKVNAVSRGRQHERAQFHISGDDEDSNVHRQE 360 361 SRASNTSPNVSLPPIKSILRQIDNFNSAPSYFSK |
Interface Residues: | 3, 5, 6, 25, 26, 27, 28, 29, 30, 31, 33, 34, 35, 36, 37, 40, 57, 58, 59, 60, 61, 62, 63, 64, 65, 68, 84, 85, 86, 87, 90, 91, 92, 257, 259, 268 |
3D-footprint Homologues: | 6wmi_A, 2lt7_A, 6ml4_A, 5und_A, 5kkq_D, 8ssu_A, 6jnm_A, 3uk3_C, 2kmk_A, 8ssq_A, 7w1m_H, 8cuc_F, 1g2f_F, 7y3l_A, 5ei9_F, 8h9h_G, 1mey_C, 2drp_D, 7ysf_A, 1f2i_J, 7eyi_G, 6a57_A, 5k5i_A, 5v3j_F, 7n5w_A, 6blw_A, 6u9q_A, 5yel_A, 4x9j_A, 2i13_A, 8gn3_A, 1llm_D, 7txc_E, 5kl3_A, 1ubd_C, 4m9v_C, 1tf3_A, 1tf6_A, 6e94_A, 7y3m_I, 2jpa_A, 2gli_A, 2wbs_A, 5yj3_D, 7u5d_E |
Binding Motifs: | M0511_1.02 rTGCGGGGkt MA0339.1 CCCCrCa MA0339.2 CCCCrC |
Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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