Transcription Factor

						

			
Accessions: Q06416 (JASPAR 2024)

			
Names: Oct4-pg1, Octamer-binding protein 3-like, Octamer-binding transcription factor 3-like, P5F1B_HUMAN, Putative POU domain, class 5, transcription factor 1B
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q06416
Length: 359
Pfam Domains:   141-212 Pou domain - N-terminal to homeobox domain
  231-286 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI   60
  61 PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG  120
 121 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS  180
 181 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR  240
 241 VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA  300
 301 GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
Interface Residues: 164, 180, 181, 182, 183, 185, 186, 192, 196, 230, 231, 232, 233, 234, 235, 271, 274, 275, 278, 279, 281, 282, 283, 286
3D-footprint Homologues: 7u0g_M, 3l1p_A, 3d1n_M, 1au7_A, 2xsd_C, 7xrc_C, 1o4x_A, 8g87_X, 1e3o_C, 3a01_E, 6a8r_A, 1fjl_B, 1ig7_A, 3cmy_A, 2h1k_B, 1zq3_P, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 5hod_A, 5jlw_D, 1le8_A, 7q3o_C, 4cyc_A, 1b72_A, 6es3_K, 4qtr_D, 2d5v_B, 1du0_A, 6m3d_C, 4xrs_G, 5zjt_E, 2r5y_A, 1puf_A, 5flv_I, 2hdd_A, 2hos_A, 3vw3_H
Binding Motifs: MA0792.1 TATGywAAT
			
Publications: Ingraham H. A., Flynn S. E., Voss J. W., Albert V. R., Kapiloff M. S., Wilson L., Rosenfeld M. G. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell 61:1021-1033 (1990). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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