Transcription Factor
| Accessions: | G5EFF5 (JASPAR 2024) |
| Names: | Abnormal dauer formation protein 12, DAF12_CAEEL, Nuclear hormone receptor family member daf-12 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | G5EFF5 |
| Length: | 753 |
| Pfam Domains: | 116-185 Zinc finger, C4 type (two domains) |
| Sequence: (in bold interface residues) | 1 MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM 60 61 STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV 120 121 CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT 180 181 VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP 240 241 PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT 300 301 MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM 360 361 NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP 420 421 GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM 480 481 IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ 540 541 MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV 600 601 TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV 660 661 YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG 720 721 LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK |
| Interface Residues: | 126, 127, 129, 130, 136, 137, 139, 140, 143, 144, 168, 195, 196, 198, 201 |
| 3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B |
| Binding Motifs: | MA0538.1 GwGyGyGtkTGyktb MA0538.2 GwGyGyGtkTGykt |
| Binding Sites: | MA0538.1.1 MA0538.1.10 / MA0538.1.11 MA0538.1.12 MA0538.1.13 MA0538.1.14 MA0538.1.15 MA0538.1.16 MA0538.1.17 MA0538.1.18 MA0538.1.19 MA0538.1.2 / MA0538.1.3 / MA0538.1.4 MA0538.1.20 MA0538.1.5 MA0538.1.6 / MA0538.1.8 MA0538.1.7 / MA0538.1.9 MA0538.2.1 MA0538.2.10 / MA0538.2.11 MA0538.2.12 MA0538.2.13 MA0538.2.14 MA0538.2.15 MA0538.2.16 MA0538.2.17 MA0538.2.18 MA0538.2.19 MA0538.2.2 / MA0538.2.3 / MA0538.2.4 MA0538.2.20 MA0538.2.5 MA0538.2.6 / MA0538.2.8 MA0538.2.7 / MA0538.2.9 |
| Publications: | Ao W, Gaudet J, Kent W.J, Muttumu S, Mango S.E. Environmentally induced foregut remodeling by PHA-4/FoxA and DAF-12/NHR. Science (New York, N.Y.) 305:1743-6 (2004). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.