Transcription Factor

Accessions: P51960 (JASPAR 2024)
Names: A-Myb, Myb-like protein 1, Myb-related protein A, MYBA_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P51960
Length: 751
Pfam Domains: 35-81 Myb-like DNA-binding domain
38-98 Myb-like DNA-binding domain
87-133 Myb-like DNA-binding domain
90-147 Myb-like DNA-binding domain
139-183 Myb-like DNA-binding domain
142-195 Myb-like DNA-binding domain
240-285 LMSTEN motif
485-648 C-myb, C-terminal
Sequence:
(in bold interface residues)
1 MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTL 60
61 IASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGR 120
121 IGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHW 180
181 NSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCATMDHLQTQNQFYIPVQIPGYQYVSPDG 240
241 NCVEHVQTSAFIQQPFVDEDPDKEKKIKELELLLMSAENEVRRKRLPPQPGSFSSWSGSF 300
301 LMDDSMSNTLNNLEEHTTEFYSMDENQTVSAQQNSPTKFLAVEANAVLSSLQTIPEFPRT 360
361 LELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNS 420
421 RNGGDSEAIPLTSPNVVKFSTPPTISRKKKRIRVGQSAGSELGSASLSEVGNRRIKHTPV 480
481 KTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKVLITTPLQKEATPKDQKENVGFRT 540
541 PTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDIFL 600
601 KEEDEPAYKSCKQEHSASVKKVRKSLALESWDKEEPGTQLLTEDISDMQSENILTTSLLM 660
661 IPLLEIHDNRCNLTPEKQDINSANKTYTLNKKRPNPNPCKAVKLEKSLQSNCEWETVVYG 720
721 KTEDQLIMTEQARRYLSTYTATSSTSRALIL
Interface Residues: 35, 70, 71, 74, 75, 78, 79, 80, 87, 121, 122, 123, 124, 126, 127, 130, 131, 132, 173, 174, 177, 178, 181, 182, 183
3D-footprint Homologues: 1w0t_A, 5eyb_B, 3osg_A, 7xur_A, 1vfc_A, 2kdz_A, 6kks_A, 1mse_C, 3zqc_A
Binding Motifs: PB0046.1 ttgawAACCGTTAwwhw
PB0150.1 bsaCCAACTGcCgwk
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.