Transcription Factor

						

			
Accessions: ZNF264 (humanC2H2ZF-ChIP Feb2015), O43296 (JASPAR 2024)

			
Names: ENSG00000083844, O43296, ZNF264, ZN264_HUMAN
Organisms: Homo sapiens
Libraries: humanC2H2ZF-ChIP Feb2015 1, JASPAR 2024 2
1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: TF family: C2H2;KRAB experiment: ChIP-seq/MEME/B1H-RC
Length: 627
Pfam Domains:     14-54 KRAB box
  203-225 C2H2-type zinc finger
  203-225 Zinc finger, C2H2 type
  203-213 C2H2-type zinc finger
  221-240 Zinc-finger double domain
  230-242 C2H2-type zinc finger
  231-252 C2H2-type zinc finger
  231-253 Zinc finger, C2H2 type
  245-269 Zinc-finger double domain
  258-279 C2H2-type zinc finger
  259-281 C2H2-type zinc finger
  259-281 Zinc finger, C2H2 type
  274-298 Zinc-finger double domain
  286-309 C2H2-type zinc finger
  287-305 C2H2-type zinc finger
  287-309 Zinc finger, C2H2 type
  301-326 Zinc-finger double domain
  315-333 C2H2-type zinc finger
  315-337 C2H2-type zinc finger
  330-354 Zinc-finger double domain
  342-365 C2H2-type zinc finger
  343-365 Zinc finger, C2H2 type
  343-365 C2H2-type zinc finger
  358-381 Zinc-finger double domain
  370-380 C2H2-type zinc finger
  371-391 C2H2-type zinc finger
  388-410 Zinc-finger double domain
  399-421 C2H2-type zinc finger
  399-410 C2H2-type zinc finger
  399-421 Zinc finger, C2H2 type
  414-438 Zinc-finger double domain
  427-449 Zinc finger, C2H2 type
  427-449 C2H2-type zinc finger
  445-466 Zinc-finger double domain
  455-477 Zinc finger, C2H2 type
  455-475 C2H2-type zinc finger
  455-473 C2H2-type zinc finger
  470-494 Zinc-finger double domain
  482-505 C2H2-type zinc finger
  483-505 Zinc finger, C2H2 type
  483-505 C2H2-type zinc finger
  498-520 Zinc-finger double domain
  510-529 C2H2-type zinc finger
  511-533 Zinc finger, C2H2 type
  525-550 Zinc-finger double domain
  538-561 C2H2-type zinc finger
  539-561 C2H2-type zinc finger
  539-561 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MAAAVLTDRAQVSVTFDDVAVTFTKEEWGQLDLAQRTLYQEVMLENCGLLVSLGCPVPKA   60
  61 ELICHLEHGQEPWTRKEDLSQDTCPGDKGKPKTTEPTTCEPALSEGISLQGQVTQGNSVD  120
 121 SQLGQAEDQDGLSEMQEGHFRPGIDPQEKSPGKMSPECDGLGTADGVCSRIGQEQVSPGD  180
 181 RVRSHNSCESGKDPMIQEEENNFKCSECGKVFNKKHLLAGHEKIHSGVKPYECTECGKTF  240
 241 IKSTHLLQHHMIHTGERPYECMECGKAFNRKSYLTQHQRIHSGEKPYKCNECGKAFTHRS  300
 301 NFVLHNRRHTGEKSFVCTECGQVFRHRPGFLRHYVVHSGENPYECLECGKVFKHRSYLMW  360
 361 HQQTHTGEKPYECSECGKVFLESAALIHHYVIHTGEKPFECLECGKAFNHRSYLKRHQRI  420
 421 HTGEKPFVCSECGKAFTHCSTFILHKRAHTGEKPFECKECGKAFSNRKDLIRHFSIHTGE  480
 481 KPYECVECGKAFTRMSGLTRHKRIHSGEKPYECVECGKSFCWSTNLIRHAIIHTGEKPYK  540
 541 CSECGKAFSRSSSLTQHQRMHTGKNPISVTDVGRPFTSGQTSVTLRELLLGKDFLNVTTE  600
 601 ANILPEETSSSASDQPYQRETPQVSSL
Interface Residues: 214, 216, 220, 231, 241, 242, 243, 244, 245, 269, 270, 271, 272, 273, 276, 280, 298, 299, 300, 301, 303, 304, 308, 326, 327, 328, 329, 331, 332, 354, 355, 356, 357, 360, 382, 383, 384, 385, 387, 388, 409, 410, 412, 413, 416, 422, 436, 437, 438, 439, 440, 441, 443, 444, 445, 446, 447, 448, 450, 465, 466, 467, 468, 469, 470, 471, 472, 473, 476, 493, 494, 495, 496, 497, 499, 500, 521, 522, 523, 524, 525, 527, 528, 550, 551, 552, 553, 555, 556
3D-footprint Homologues: 7w1m_H, 2kmk_A, 6jnm_A, 3uk3_C, 2wbs_A, 5yj3_D, 8ssq_A, 8ssu_A, 7y3m_I, 6a57_A, 5v3j_F, 5yel_A, 5und_A, 6ml4_A, 1tf6_A, 2i13_A, 5kl3_A, 8cuc_F, 7y3l_A, 6wmi_A, 1g2f_F, 5kkq_D, 6u9q_A, 4m9v_C, 7ysf_A, 6e94_A, 2jpa_A, 1tf3_A, 7n5w_A, 5ei9_F, 5k5i_A, 2gli_A, 8gn3_A, 1llm_D, 7txc_E, 7eyi_G, 8h9h_G, 1ubd_C, 1mey_C, 6blw_A, 4x9j_A, 2lt7_A, 2drp_D, 1f2i_J
Binding Motifs: ZNF264_ChIP AAGGGCACTAATCCC
UN0605.1 srGGmkGgG
UN0605.2 GGmkGgG
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.