Transcription Factor
| Accessions: | Q16236 (JASPAR 2024) |
| Names: | HEBP1, NF-E2-related factor 2, NF2L2_HUMAN, NFE2-related factor 2, Nrf-2, Nuclear factor erythroid 2-related factor 2, Nuclear factor, erythroid derived 2, like 2 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 605 |
| Pfam Domains: | 499-556 bZIP transcription factor 502-542 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKEYELEKQKKLEKERQE 60 61 QLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDALYFDDCM 120 121 QLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGM 180 181 QQDIEQVWEELLSIPELQCLNIENDKLVETTMVPSPEAKLTEVDNYHFYSSIPSMEKEVG 240 241 NCSPHFLNAFEDSFSSILSTEDPNQLTVNSLNSDATVNTDFGDEFYSAFIAEPSISNSMP 300 301 SPATLSHSLSELLNGPIDVSDLSLCKAFNQNHPESTAEFNDSDSGISLNTSPSVASPEHS 360 361 VESSSYGDTLLGLSDSEVEELDSAPGSVKQNGPKTPVHSSGDMVQPLSPSQGQSTHVHDA 420 421 QCENTPEKELPVSPGHRKTPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVVD 480 481 FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLL 540 541 KEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKP 600 601 DVKKN |
| Interface Residues: | 503, 507, 508, 510, 511, 514, 515, 518 |
| 3D-footprint Homologues: | 1skn_P, 2wt7_A, 7x5e_E, 2wt7_B, 7x5e_F, 5vpe_D, 5t01_B |
| Binding Motifs: | MA0150.1 rTGACwmAGCA |
| Binding Sites: | MA0150.1.1 MA0150.1.10 MA0150.1.11 MA0150.1.12 MA0150.1.13 MA0150.1.14 MA0150.1.15 MA0150.1.16 MA0150.1.17 MA0150.1.18 MA0150.1.19 MA0150.1.2 MA0150.1.20 MA0150.1.3 MA0150.1.4 MA0150.1.5 MA0150.1.6 MA0150.1.7 MA0150.1.8 MA0150.1.9 |
| Publications: | Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.