Transcription Factor

Accessions: T049306_1.02 (CISBP 1.02), Q08376 (JASPAR 2024)
Names: T049306_1.02;, Zfp161, ZBT14_MOUSE, ZF5, Zfp-161, Zinc finger and BTB domain-containing protein 14, Zinc finger protein 161, Zinc finger protein 5
Organisms: Mus musculus
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 449
Pfam Domains: 26-127 BTB/POZ domain
278-299 C2H2-type zinc finger
279-299 Zinc finger, C2H2 type
292-316 Zinc-finger double domain
305-325 Zinc-finger of C2H2 type
305-327 C2H2-type zinc finger
305-327 Zinc finger, C2H2 type
319-342 Zinc-finger double domain
333-353 Zinc-finger of C2H2 type
333-355 C2H2-type zinc finger
333-355 Zinc finger, C2H2 type
347-372 Zinc-finger double domain
361-383 Zinc finger, C2H2 type
361-381 Zinc-finger of C2H2 type
361-383 C2H2-type zinc finger
375-399 Zinc-finger double domain
389-412 Zinc finger, C2H2 type
389-412 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY 60
61 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL 120
121 DKLCSQKRDVSSPDESNGQSKSKYCLKLNRPIGDAADAQDDDVEEIGDQDDSPSDDTVEG 180
181 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT 240
241 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT 300
301 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP 360
361 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP 420
421 SAIQSETEQLQAAAMAAEAEQQLETIACS
Interface Residues: 287, 288, 289, 290, 291, 294, 298, 305, 315, 316, 317, 318, 319, 321, 322, 323, 324, 325, 326, 328, 343, 344, 345, 346, 347, 348, 349, 350, 351, 353, 354, 371, 372, 373, 374, 375, 376, 377, 378, 399, 400, 401, 402, 403, 405, 406
3D-footprint Homologues: 6jnm_A, 8cuc_F, 1tf3_A, 7y3l_A, 5v3j_F, 7n5w_A, 5kkq_D, 1tf6_A, 6u9q_A, 4x9j_A, 6wmi_A, 8ssq_A, 7w1m_H, 8ssu_A, 1g2f_F, 8h9h_G, 7y3m_I, 2i13_A, 6a57_A, 2kmk_A, 3uk3_C, 1llm_D, 7txc_E, 5yj3_D, 5ei9_F, 1mey_C, 5und_A, 5k5i_A, 6ml4_A, 2gli_A, 8gn3_A, 6blw_A, 7eyi_G, 4m9v_C, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 5yel_A, 5kl3_A, 2wbs_A, 1f2i_J, 2lt7_A, 2drp_D
Binding Motifs: PB0199.1 gyCGCGCArkGCrt
M0432_1.02 srCGyGcmy
PB0095.1 kgrcGCGCGCryyyrw
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.