Transcription Factor
| Accessions: | ATF2 (HT-SELEX2 May2017) |
| Names: | ATF2, ENSG00000115966 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4 |
| Length: | 425 |
| Pfam Domains: | 343-396 Basic region leucine zipper 344-403 bZIP transcription factor |
| Sequence: (in bold interface residues) | 1 SARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARNDSVIVADQ 60 61 TPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIRSKIEEPSV 120 121 VETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQA 180 181 VPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVPL 240 241 VRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSE 300 301 ESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASR 360 361 CRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSG 420 421 YHTAD |
| Interface Residues: | 30, 31, 32, 33, 35, 36, 38, 39, 40, 348, 349, 350, 354, 355, 357, 358, 361, 362 |
| 3D-footprint Homologues: | 5ei9_F, 2i13_A, 7n5w_A, 8cuc_F, 6jnm_A, 5kl3_A, 5yj3_D, 1ubd_C, 8h9h_G, 6wmi_A, 2wbs_A, 1f2i_J, 7y3l_A, 6a57_A, 4x9j_A, 2gli_A, 7eyi_G, 1mey_C, 7y3m_I, 6blw_A, 1tf3_A, 2jpa_A, 2wt7_B, 4eot_A, 7x5e_E, 2wt7_A, 5vpe_D, 1dh3_C, 5t01_B, 5vpe_C |
| Binding Motifs: | ATF2_2 srTkACGTmAys ATF2_4 srTGACGTmays ATF2_methyl_1 grTGAyGTmAys ATF2_methyl_3 grTGAyGTmAys |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.