Transcription Factor

Accessions: JUND (SMILE-seq 1.0)
Names: JUND, JUND_HUMAN
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: P17535
Notes: TF family: bZIP
Length: 303
Pfam Domains: 1-214 Jun-like transcription factor
223-285 bZIP transcription factor
228-283 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MMKKDALTLSLSEQVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPEL 60
61 ERLIIQSNGLVTTTPTSSQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAA 120
121 AAAGGPSGTATGSAPPGELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFP 180
181 PPPPPGALGPPRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAAS 240
241 KCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQ 300
301 VPA
Interface Residues: 231, 232, 235, 236, 238, 239, 242, 243, 246
3D-footprint Homologues: 4eot_A, 7x5e_F, 2wt7_A, 2wt7_B, 1skn_P, 1nwq_C, 1dh3_C, 2dgc_A, 5t01_B, 1gd2_G, 5vpe_C, 5vpe_D
Binding Motifs: JUND_1 krTGmGTCAT
JUND_2 aTGACGTmAtc
JUND_FOSB_1 taTgActmAtw
JUND_FOSL1_1 rrTGActmAt
JUND_FOSL1_2 rTGACgymay
JUND_FOSL2_1 krTGAsTCAy
JUND_FOSL2_2 kkrTkACGTCAycgc
JUND_FOS_1 kkrTGAGTCAymv
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

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