Transcription Factor

						

			
Accessions: 5tw1_F (3D-footprint 20231221)

			
Names: A0QW02_MYCS2, RNA polymerase sigma factor SigA
Organisms: Mycobacterium smegmatis, Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: A0QW02
Length: 302
Pfam Domains:      1-35 Sigma-70 factor, region 1.2
   71-141 Sigma-70 region 2 
  150-224 Sigma-70 region 3
  237-290 Sigma-70, region 4
Sequence: 
(in bold interface residues)		   1 ADSVRAYLKQIGKVALLNAEEEVELAKRIEAGLYATQKLAELAEKGEKLPVQQRRDMQWI   60
  61 CRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFS  120
 121 TYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMD  180
 181 ITPEKVLEIQQYAREPISLDQTIGDDSQLGDFIEDSEAVVAVDAVSFTLLQDQLQSVLET  240
 241 LSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDY  300
 301 LD
Interface Residues: 263, 264, 273, 274, 275, 276, 278, 279
3D-footprint Homologues: 6ido_B, 3n97_A, 8cyf_B
Binding Motifs: 5tw1_F CTTGACAnnnnnnnnnnnnTnTGCT
Binding Sites: 5tw1_O
5tw1_P
			
Publications: Hubin EA, Fay A, Xu C, Bean JM, Saecker RM, Glickman MS, Darst SA, Campbell EA. Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA. Elife : (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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