Transcription Factor
Accessions: | Q9NQ69 (JASPAR 2024) |
Names: | LHX9_HUMAN, LIM homeobox protein 9, LIM/homeobox protein Lhx9 |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q9NQ69 |
Length: | 397 |
Pfam Domains: | 71-128 LIM domain 133-188 LIM domain 268-324 Homeobox domain |
Sequence: (in bold interface residues) | 1 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM 60 61 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC 120 121 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL 180 181 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV 240 241 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL 300 301 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT 360 361 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF |
Interface Residues: | 267, 268, 269, 270, 271, 309, 310, 312, 313, 316, 317, 320, 321, 324 |
3D-footprint Homologues: | 3d1n_M, 1ig7_A, 1nk2_P, 5zfz_A, 2h1k_B, 1puf_A, 3cmy_A, 1fjl_B, 6a8r_A, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 2r5y_A, 6es3_K, 2ld5_A, 7q3o_C, 7psx_B, 1b72_A, 5jlw_D, 4cyc_A, 4xrs_G, 3l1p_A, 4j19_B, 3a01_E, 5flv_I, 5zjt_E, 2hdd_A, 5hod_A, 3rkq_B, 1puf_B, 2hos_A, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 1le8_B, 1du0_A, 6fqq_E, 4qtr_D, 8g87_X, 4xrm_B |
Binding Motifs: | MA0701.1 cyAATTAr MA0701.2 CyAATTAr MA0701.3 CyAATTA |
Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.