Transcription Factor

Accessions: Atf4_DBD (HumanTF 1.0)
Names: Activating transcription factor 4, Atf4, ATF4_MOUSE, C/ATF, C/EBP-related ATF, cAMP-dependent transcription factor ATF-4, Cyclic AMP-dependent transcription factor ATF-4, Tax-responsive enhancer element-binding protein 67 homolog, TaxREB67 homolog
Organisms: Mus musculus
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q06507
Notes: Ensembl ID: ENSMUSG00000042406; DNA-binding domain sequence; TF family: bZIP; Clone source: Hughes lab.
Length: 91
Pfam Domains: 16-77 bZIP transcription factor
19-70 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 PYDPPGVSLTAKVKTEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEAL 60
61 KEKADSLAKEIQYLKDLIEEVRKARGKKRVP
Interface Residues: 28, 29, 31, 32, 35, 36
3D-footprint Homologues: 2wt7_A, 6mg1_B
Binding Motifs: Atf4_DBD aggATGAYGCAATm
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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