Transcription Factor

Accessions: T061541_1.02 (CISBP 1.02), P39959 (JASPAR 2024)
Names: T061541_1.02;, YER130C, YEW0_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 443
Pfam Domains: 390-412 Zinc finger, C2H2 type
391-412 C2H2-type zinc finger
391-410 Zinc-finger of C2H2 type
403-428 Zinc-finger double domain
418-440 C2H2-type zinc finger
418-440 Zinc finger, C2H2 type
418-438 Zinc-finger of C2H2 type
Sequence:
(in bold interface residues)
1 MSLYPLQRFESNDTVFSYTLNSKTELFNESRNNDKQHFTLQLIPNANANAKEIDNNNVEI 60
61 INDLTGNTIVDNCVTTATSSNQLERRLSISDYRTENGNYYEYEFFGRRELNEPLFNNDIV 120
121 ENDDDIDLNNESDVLMVSDDELEVNERFSFLKQQPLDGLNRISSTNNLKNLEIHEFIIDP 180
181 TENIDDELEDSFTTVPQSKKKVRDYFKLNIFGSSSSSNNNSNSLGCEPIQTENSSSQKMF 240
241 KNRFFRSRKSTLIKSLPLEQENEVLINSGFDVSSNEESDESDHAIINPLKLVGNNKDIST 300
301 QSIAKTTNPFKSGSDFKMIEPVSKFSNDSRKDLLAAISEPSSSPSPSAPSPSVQSSSSSH 360
361 GLVVRKKTGSMQKTRGRKPSLIPDASKQFGCEFCDRRFKRQEHLKRHVRSLHMCEKPFTC 420
421 HICNKNFSRSDNLNQHVKTHASL
Interface Residues: 372, 374, 375, 378, 399, 400, 401, 402, 403, 405, 406, 407, 410, 411, 414, 415, 428, 429, 430, 431, 432, 433, 434, 435, 436, 439
3D-footprint Homologues: 1ubd_C, 3uk3_C, 8cuc_F, 2kmk_A, 7y3l_A, 2i13_A, 8h9h_G, 1llm_D, 6blw_A, 5kkq_D, 2wbs_A, 7ysf_A, 6wmi_A, 5yel_A, 5ei9_F, 2jpa_A, 1mey_C, 5kl3_A, 2drp_D, 1f2i_J, 7eyi_G, 5k5i_A, 8ssu_A, 1tf6_A, 6ml4_A, 5und_A, 2gli_A, 8gn3_A, 1g2f_F, 7n5w_A, 5k5l_F, 2lt7_A, 6u9q_A, 5v3j_F, 4x9j_A, 4m9v_C, 8ssq_A, 7w1m_H, 6e94_A, 7y3m_I, 1yuj_A, 7txc_E, 5yj3_D, 6a57_A
Binding Motifs: M0513_1.02 AtAGGGGg
MA0423.1 mCCCCTwTh
MA0423.2 CCCCTwT
Publications: Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST

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