Transcription Factor

Accessions: P23758 (JASPAR 2024)
Names: Paired box neuronal protein, Paired box pox-neuro protein, POXN_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 425
Pfam Domains: 5-130 'Paired box' domain
Sequence:
(in bold interface residues)
1 MPHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTR 60
61 FYETGSIRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVP 120
121 SISSINRILRNSGLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVA 180
181 PPTPAATPSIARYAKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGLDLSYSA 240
241 LHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLPHAMAAAAASSTSALGGFTKSE 300
301 SSIDLSTPGAAGDALSDCDSGKSSPAALSLTASGGGNGAGSAPEASPGSTLSHSRKRNPY 360
361 SIEELLKKPEKRLRLDSNRLECLESSSCESSQDSPVAPPLETPEDEDPAEAEEEQEEEDS 420
421 VEVVN
Interface Residues: 18, 50, 51, 53, 55, 56, 72, 75, 78, 121, 122, 123, 124, 126, 127, 130
3D-footprint Homologues: 6pax_A, 1k78_A, 1pdn_C
Binding Motifs: MA0239.1 wgtAACwGt
UN0783.1 rsCGTGACG
Binding Sites: MA0239.1.1
MA0239.1.10
MA0239.1.11
MA0239.1.12
MA0239.1.13
MA0239.1.14
MA0239.1.15
MA0239.1.16
MA0239.1.17
MA0239.1.18
MA0239.1.19
MA0239.1.2
MA0239.1.20
MA0239.1.3
MA0239.1.4
MA0239.1.5
MA0239.1.6
MA0239.1.7
MA0239.1.8
MA0239.1.9
Publications: Meng X, Brodsky M.H, Wolfe S.A. A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors. Nature biotechnology 23:988-94 (2005). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.