Transcription Factor

						

			
Accessions: ARNTL_DBD (HumanTF 1.0)

			
Names: ARNTL, B2RCL8_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: B2RCL8
Notes: Ensembl ID: ENSG00000133794; DNA-binding domain sequence; TF family: bHLH; Clone source: Megaman
Length: 129
Pfam Domains:    45-101 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MAPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRAAYTRQQVLELE   60
  61 KEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP  120
 121 STLSAATPG
Interface Residues: 6, 7, 8, 11, 12, 45, 46, 47, 48, 86, 87, 89, 90, 93, 94, 97, 98, 101
3D-footprint Homologues: 3d1n_M, 6a8r_A, 2h1k_B, 1puf_A, 1fjl_B, 3cmy_A, 5zfz_A, 1nk2_P, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 2ld5_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3a01_E, 7q3o_C, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 1b72_A, 3rkq_B, 2r5y_A, 1ig7_A, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 8g87_X, 1du0_A, 3l1p_A, 1o4x_A, 4qtr_D, 1mnm_C, 1puf_B
Binding Motifs: ARNTL_DBD GTCACGTGAC
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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