Transcription Factor
| Accessions: | ECK120006834 (RegulonDB 7.5) |
| Names: | Dan |
| Organisms: | ECK12 |
| Libraries: | RegulonDB 7.5 1 1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed] |
| Notes: | transcription repressor activity; Transcription related; sequence-specific DNA binding transcription factor activity; transcription activator activity; positive regulation of transcription, DNA-dependent; repressor; activator |
| Length: | 311 |
| Pfam Domains: | 9-67 Bacterial regulatory helix-turn-helix protein, lysR family 92-296 LysR substrate binding domain |
| Sequence: (in bold interface residues) | 1 MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGV 60 61 ALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMR 120 121 NYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYP 180 181 QPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG 240 241 IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRL 300 301 GKPDEGYQVM* |
| Interface Residues: | 33, 34, 35, 36, 38, 39, 57 |
| 3D-footprint Homologues: | 1r71_B, 5xxp_A, 7d98_Q |
| Binding Motifs: | Dan GTTaATT |
| Binding Sites: | ECK125109294 ECK125109299 ECK125109301 ECK125109303 ECK125109305 |
| Publications: | Oshima T., Biville F. Functional identification of ygiP as a positive regulator of the ttdA-ttdB-ygjE operon. Microbiology. 152(Pt 7):2129-35 (2006). [Pubmed] Teramoto J., Yoshimura SH., Takeyasu K., Ishihama A. A novel nucleoid protein of Escherichia coli induced under anaerobiotic growth conditions. Nucleic Acids Res. 38(11):3605-18 (2010). [Pubmed] Kim OB., Reimann J., Lukas H., Schumacher U., Grimpo J., Dunnwald P., Unden G. Regulation of tartrate metabolism by TtdR and relation to the DcuS-DcuR-regulated C4-dicarboxylate metabolism of Escherichia coli. Microbiology. 155(Pt 11):3632-40 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.