Transcription Factor
| Accessions: | T061408_1.02 (CISBP 1.02), G5EDU4 (JASPAR 2024) |
| Names: | eor-1, T061408_1.02;, G5EDU4_CAEEL |
| Organisms: | Caenorhabditis elegans |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | G5EDU4 |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 909 |
| Pfam Domains: | 33-135 BTB/POZ domain 142-241 BTB And C-terminal Kelch 426-447 C2H2-type zinc finger 540-562 C2H2-type zinc finger 567-589 Zinc finger, C2H2 type 567-589 C2H2-type zinc finger 594-618 Zinc finger, C2H2 type 625-646 C2H2-type zinc finger 626-646 Zinc finger, C2H2 type 638-662 Zinc-finger double domain 652-675 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MTLVASSENTGLCPMTFDDSSGQTSHMLFQRLQYQRKTGRFCDVEIVVQNKSFAAHRNIL 60 61 AAHSPYFDAIFKYCKITKEQLTINSKSPQVFELFLNYMYSGTVIIDRSSVSELLRFANNF 120 121 LIVKLKVYCAAYLDRYLDAANCLSIRTLAQRYNLPGLVKSATDYFDSNLNRCLLESRDII 180 181 GYTYTQLTRLIGDPKYVDCITSDTYLKLIVRWVGEEVSKREEIFRLLLESCEFREVSADT 240 241 LEFLLDYSPLLSKSQKSRFLLLHVMETNNMLMEKYSTQLSSLRQKIVDLPILHDPSQFED 300 301 DIYDSSDSEEDPDDYIADGHPTSAQVVEYGNDVNNRLKMKIAFQPGNEKKRLKRPKGMKK 360 361 HHLHPIPPINATENESIPWIDEDEIDGVYATCSLEGCHTYGPVDNLDPDDCEDEEDQPDE 420 421 NGPSTCIFCGLRTANEELLEKHKARHHNRNTYYMCHLCEFETNWSKQFYLHCAEHWTEIP 480 481 YRCETCPFTSNEIQEFLTHRLQHTDERFFKCGECAWKGRTRSQLFAHERMHSVLDDRSLH 540 541 CEECGRGFQQHSTLDHHVASHNDPRPYICEDCGFATKTADHLSLHRRQHTGDNFSCHIAG 600 601 CDYSSTKKSQLAAHLRTHMAVRAHLCKICGRGFIEKSHLVRHERIHLEEKPFKCDQCEYA 660 661 SSRRDKLKEHIIKHHNSEVLTFQKTQRRKYKRQRMLAAASNIVNNPDALFRPITSDDAVS 720 721 NWQATNDFSTYSPNPNDYGGPSTYGNPSSPQRAFSVVHPSQHQHHAQSPGCMSMMNVPLR 780 781 DNHHQMQRQDSPGDSVGGGQGGGGGGGPEGSDNTHGVLMTPNLVMRSPHNRSAVQPQFNN 840 841 LSTNSDPQQQQQQQQLRPFSLPTYGQMDLAQAAQLQQLQQQLQAAGLPPTGTPNNQDNSN 900 901 NAWNPWNVQ |
| Interface Residues: | 462, 464, 465, 492, 494, 495, 498, 501, 520, 521, 522, 523, 526, 529, 539, 549, 550, 551, 552, 553, 556, 578, 579, 580, 581, 583, 584, 586, 587, 588, 589, 590, 604, 605, 606, 607, 608, 609, 610, 611, 613, 634, 635, 636, 637, 638, 640, 641, 642, 659, 661, 662, 663, 664, 665, 666, 667, 668, 669, 670, 673, 687, 704 |
| 3D-footprint Homologues: | 1tf6_A, 8ssq_A, 5und_A, 8ssu_A, 5yel_A, 1mey_C, 7w1m_H, 2kmk_A, 6wmi_A, 5v3j_F, 5ei9_F, 7ysf_A, 2i13_A, 7y3m_I, 2gli_A, 6ml4_A, 5kkq_D, 6u9q_A, 7eyi_G, 6e94_A, 2jpa_A, 1tf3_A, 7n5w_A, 5k5l_F, 4x9j_A, 8gn3_A, 1g2f_F, 6blw_A, 5kl3_A, 8h9h_G, 1ubd_C, 3uk3_C, 6jnm_A, 8cuc_F, 7y3l_A, 5k5i_A, 1f2i_J, 2wbs_A, 1llm_D, 7txc_E, 4m9v_C, 2lt7_A, 6a57_A, 5yj3_D |
| Binding Motifs: | MA0543.1 rrAGAGAsrsAGAsA M0488_1.02 grGGGRtc MA0543.2 AGAGAsrsAGAsA |
| Binding Sites: | MA0543.1.1 MA0543.1.10 MA0543.1.11 MA0543.1.12 MA0543.1.13 MA0543.1.14 MA0543.1.15 MA0543.1.16 MA0543.1.17 MA0543.1.18 MA0543.1.19 MA0543.1.2 MA0543.1.20 MA0543.1.3 MA0543.1.4 MA0543.1.5 MA0543.1.6 MA0543.1.7 MA0543.1.8 MA0543.1.9 MA0543.2.1 MA0543.2.10 MA0543.2.11 MA0543.2.12 MA0543.2.13 MA0543.2.14 MA0543.2.15 MA0543.2.16 MA0543.2.17 MA0543.2.18 MA0543.2.19 MA0543.2.2 MA0543.2.20 MA0543.2.3 MA0543.2.4 MA0543.2.5 MA0543.2.6 MA0543.2.7 MA0543.2.8 MA0543.2.9 |
| Publications: | Hoeppner D.J, Spector M.S, Ratliff T.M, Kinchen J.M, Granat S, Lin S.C, Bhusri S.S, Conradt B, Herman M.A, Hengartner M.O. eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans. Developmental biology 274:125-38 (2004). [Pubmed] |
| Related annotations: | PaperBLAST |
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