Transcription Factor

Accessions: Q00958 (JASPAR 2024), LEAFY (EEADannot 2023-12-22)
Names: LFY_ARATH, LEAFY, LEAFY3, LFY, LFY3
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, EEADannot 2023-12-22 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 Contreras-Moreira B, Sebastian A. FootprintDB: Analysis of Plant Cis-Regulatory Elements, Transcription Factors, and Binding Interfaces. Methods Mol Biol 1482:259-77 (2016) [Pubmed]
Uniprot: Q00958
Notes: family:Floricaula/leafy
Length: 420
Pfam Domains: 1-390 Floricaula / Leafy protein
Sequence:
(in bold interface residues)
1 MDPEGFTSGLFRWNPTRALVQAPPPVPPPLQQQPVTPQTAAFGMRLGGLEGLFGPYGIRF 60
61 YTAAKIAELGFTASTLVGMKDEELEEMMNSLSHIFRWELLVGERYGIKAAVRAERRRLQE 120
121 EEEEESSRRRHLLLSAAGDSGTHHALDALSQEGLSEEPVQQQDQTDAAGNNGGGGSGYWD 180
181 AGQGKMKKQQQQRRRKKPMLTSVETDEDVNEGEDDDGMDNGNGGSGLGTERQREHPFIVT 240
241 EPGEVARGKKNGLDYLFHLYEQCREFLLQVQTIAKDRGEKCPTKVTNQVFRYAKKSGASY 300
301 INKPKMRHYVHCYALHCLDEEASNALRRAFKERGENVGSWRQACYKPLVNIACRHGWDID 360
361 AVFNAHPRLSIWYVPTKLRQLCHLERNNAVAAAAALVGGISCTGSSTSGRGGCGGDDLRF 420
Interface Residues: 233, 287, 302, 303, 304, 305, 307, 308
3D-footprint Homologues: 2vy1_A, 4bhk_A
Binding Motifs: MA0590.1 yATkrACCGsCGGTymATr
EEAD0005 wdrwCCAayGGwCmAwaww
EEAD0138 rrwaCAyyswwwtrycyrdwrgdya
EEAD0139 grrwaCAyyswwwtrycyr
Publications: Moyroud E, Minguet E.G, Ott F, Yant L, Posé D, Monniaux M, Blanchet S, Bastien O, Thévenon E, Weigel D, Schmid M, Parcy F. Prediction of regulatory interactions from genome sequences using a biophysical model for the Arabidopsis LEAFY transcription factor. The Plant cell 23:1293-306 (2011). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.