Transcription Factor

Accessions: T020115_1.02 (CISBP 1.02), A9TN45 (JASPAR 2018)
Names: gw1.270.82.1, T020115_1.02;, A9TN45_PHYPA, Fragment, Predicted protein
Organisms: Physcomitrella patens, moss
Libraries: CISBP 1.02 1, JASPAR 2018 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 160
Pfam Domains: 79-126 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 TSTSSVVSDGKNSKSLEANEQTSLKRQRSGLVKAERSASENSGDSASPRSLKATSKPPQD 60
61 LSKQDYIHVRARRGQATDSHSLAERVRREKISERMKFLQDLVPGCSKITGKAVMLDEIIN 120
121 YVQSLQRQIEFLSMKLAAVNPRLDYSYDLLGKDMLQSRSP
Interface Residues: 80, 81, 83, 84, 87, 88
3D-footprint Homologues: 1hlo_B, 5gnj_I, 1a0a_B, 1nkp_E, 5nj8_D, 1am9_A, 4ati_B, 5v0l_A, 4h10_A, 1an4_A
Binding Motifs: M0252_1.02 cCACGTGc
MA1021.1 cCACGTGc
Publications: Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed]

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