Transcription Factor

Accessions: T061548_1.02 (CISBP 1.02), P33400 (JASPAR 2024)
Names: RIM101, T061548_1.02;, PACC_YEAST, pH-response regulator protein RIM101, pH-response transcription factor pacC/RIM101, Regulator of IME2 protein 1
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 625
Pfam Domains: 213-234 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MVPLEDLLNKENGTAAPQHSRESIVENGTDVSNVTKKDGLPSPNLSKRSSDCSKRPRIRC 60
61 TTEAIGLNGQEDERMSPGSTSSSCLPYHSTSHLNTPPYDLLGASAVSPTTSSSSDSSSSS 120
121 PLAQAHNPAGDDDDADNDGDSEDITLYCKWDNCGMIFNQPELLYNHLCHDHVGRKSHKNL 180
181 QLNCHWGDCTTKTEKRDHITSHLRVHVPLKPFGCSTCSKKFKRPQDLKKHLKIHLESGGI 240
241 LKRKRGPKWGSKRTSKKNKSCASDAVSSCSASVPSAIAGSFKSHSTSPQILPPLPVGISQ 300
301 HLPSQQQQRAISLNQLCSDELSQYKPVYSPQLSARLQTILPPLYYNNGSTVSQGANSRSM 360
361 NVYEDGCSNKTIANATQFFTKLSRNMTNNYILQQSGGSTESSSSSGRIPVAQTSYVQPPN 420
421 APSYQSVQGGSSISATANTATYVPVRLAKYPTGPSLTEHLPPLHSNTAGGVFNRQSQYAM 480
481 PHYPSVRAAPSYSSSGCSILPPLQSKIPMLPSRRTMAGGTSLKPNWEFSLNQKSCTNDII 540
541 MSKLAIEEVDDESEIEDDFVEMLGIVNIIKDYLLCCVMEDLDDEESEDKDEENAFLQESL 600
601 EKLSLQNQMGTNSVRILTKYPKILV
Interface Residues: 158, 159, 160, 161, 162, 165, 169, 174, 176, 178, 180, 191, 193, 194, 195, 196, 197, 198, 200, 201, 202, 205, 222, 223, 224, 225, 226, 227, 228, 229, 230, 233
3D-footprint Homologues: 6jnm_A, 1tf6_A, 6wmi_A, 5ei9_F, 2i13_A, 1ubd_C, 1mey_C, 4x9j_A, 1g2f_F, 5v3j_F, 6a57_A, 7ysf_A, 6e94_A, 7w1m_H, 8ssq_A, 5yel_A, 7y3l_A, 1tf3_A, 5kl3_A, 2wbs_A, 1llm_D, 5und_A, 7eyi_G, 2jpa_A, 6ml4_A, 8gn3_A, 1f2i_J, 7n5w_A, 6blw_A, 2gli_A, 8h9h_G, 7txc_E, 2drp_D, 3uk3_C, 5k5i_A, 4m9v_C, 5kkq_D, 6u9q_A, 2kmk_A, 5yj3_D, 8cuc_F, 7y3m_I
Binding Motifs: M0524_1.02 kCTTGGCrhk
MA0368.1 yGCCAAG
Publications: Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST

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