Transcription Factor

Accessions: BARX1_DBD (HumanTF 1.0)
Names: BARX1, BARX1_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9HBU1
Notes: Ensembl ID: ENSG00000131668; DNA-binding domain sequence; TF family: homeodomain; Clone source: hDBD_G
Length: 126
Pfam Domains: 48-104 Homeobox domain
Sequence:
(in bold interface residues)
1 GLSSALLAAGPGLPGAAGAPHLPLELHVRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLM 60
61 GLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKG 120
121 RPKKNS
Interface Residues: 46, 48, 49, 50, 51, 89, 90, 92, 93, 96, 97, 100, 101, 104
3D-footprint Homologues: 1mnm_C, 1puf_A, 2h1k_B, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 1ig7_A, 5zfz_A, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 2ld5_A, 3a01_E, 5hod_A, 1puf_B, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 6es3_K, 1b72_A, 4xrs_G, 2hos_A, 4cyc_A, 2d5v_B, 5flv_I, 1e3o_C, 1au7_A, 1le8_A, 7xrc_C, 2xsd_C, 8g87_X, 5zjt_E, 4qtr_D, 7psx_B, 1k61_B, 4xrm_B, 1o4x_A, 1le8_B, 1du0_A, 3l1p_A
Binding Motifs: BARX1_DBD_1 cvATTAAawavCrATTA
BARX1_DBD_2 vcmATTAr
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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