Transcription Factor

						

			
Accessions: Q9WTP9 (JASPAR 2024)

			
Names: VAX2_MOUSE, Ventral anterior homeobox 2, Ventral retina homeodomain protein
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 292
Pfam Domains:   103-159 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MGDGGAERDRGPKRREEPGGRSGRHGEHRGAEDLRADTGSASPREIAGTSASSPAGSRES   60
  61 GGDSDGQQALGETDHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEME  120
 121 FQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATS  180
 181 NVLRLLEQGRLLSVPRAPSLLALTPGLPGLPASHRGTSLVDPRNSSPRLNPMPSASASSP  240
 241 LPPPLPAICFSSAPLLDLPAGYKLGSSAFEPYSRLEQQKVGSPGQSDKKADI
Interface Residues: 103, 104, 105, 106, 144, 145, 147, 148, 151, 152, 155, 156, 159, 168, 171
3D-footprint Homologues: 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 3d1n_M, 1fjl_B, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 1ig7_A, 3a01_E, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 1b72_A, 5hod_A, 3l1p_A, 7xrc_C, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 1o4x_A, 4qtr_D, 1le8_B, 1du0_A, 1mnm_C, 1puf_B, 1k61_B, 8g87_X
Binding Motifs: PH0175.1 kwvcryTAATTArkrc
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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