Transcription Factor

						

			
Accessions: Q91V10 (JASPAR 2024)

			
Names: Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1, Visual system homeobox 1, VSX1_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 363
Pfam Domains:   172-228 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MTGRDGLSDARSRSRALAPGCPPTGSRLRSFAINDLLGLEADLPTPAEPGLRSNSGDPAE   60
  61 AIGSGPGPGPGLCGSCPARGALPLGLGLLCGFGAQPPSAAAAARARCLLLADLRLLPSAG  120
 121 PEPAVAQGPVHPPPALGSQQRSESVSTSDGDSPSEEKNDPKMSLILGKRKKRRHRTVFTA  180
 181 HQLEELEKAFGEAHYPDVYAREMLAAKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMA  240
 241 EYGLYGAMVRHCIPLPDSVLNSADSLQGSCAPWLLGMHKKSTGMRKPESEDKLAGLWEFD  300
 301 HLKKGANKDEDGPERGPDETTQNPENSLEDVAIDLSSSSRQETKKMPPGSSTQLPQPPQV  360
 361 GAS
Interface Residues: 158, 171, 172, 173, 174, 175, 213, 214, 216, 217, 220, 221, 224, 225, 228, 229
3D-footprint Homologues: 1au7_A, 4j19_B, 5zfz_A, 1fjl_B, 2h1k_B, 1ig7_A, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 4cyc_A, 5flv_I, 3l1p_A, 1b72_A, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 7xrc_C, 2xsd_C, 1e3o_C, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D
Binding Motifs: PH0176.1 csaryTAATTAryratt
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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