Transcription Factor
| Accessions: | pnr (DrosophilaTF 1.1) |
| Names: | dGATA-A, GATA-binding factor A, PNR_DROME, Protein pannier, Transcription factor GATA-A |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] |
| Uniprot: | P52168 |
| Length: | 540 |
| Pfam Domains: | 169-202 GATA zinc finger 226-259 GATA zinc finger |
| Sequence: (in bold interface residues) | 1 MGILLSDGDSTSDQQSTRDYPHFSGDYQNVTLSAASASTSASASATHVAAVKMYHSSAVA 60 61 AYTDLAAAGSAASAGVGVGVSGYHQQAVNAPVYVPSNRQYNHVAAHFGSAAAQNAWTTEG 120 121 FGSAHAQFYSPNAAVMMGSWRSAYDPSGFQRSSPYESAMDFQFGEGRECVNCGAISTPLW 180 181 RRDGTGHYLCNACGLYHKMNGMNRPLIKPSKRLVSATATRRMGLCCTNCGTRTTTLWRRN 240 241 NDGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSAVGAGTGSGTGSTLEA 300 301 IKECKEEHDLKPSLSLERHSLSKLHTDMKSGTSSSSTLMGHHSAQQQQQQQQQQQQQQQQ 360 361 QQQQSAHQQCFPLYGQTTTQQQHQQHGHSMTSSSGQAHLSARHLHGAAGTQLYTPGSSSG 420 421 GGSASAYTSHSAETPALSNGTPSPHYQHHHHLGGTHGHHVTAAAAHHHFHAAAAVAAYGV 480 481 KTEASATNYDYVNNCYFGGTFGALGGAATTTAMAGGAASELAGYHHQHNVIQAAKLMATS 540 |
| Interface Residues: | 178, 179, 181, 191, 195, 218, 235, 236, 238, 248, 252, 253, 256, 273, 275, 276 |
| 3D-footprint Homologues: | 4hc9_A, 3vd6_C, 1gat_A, 3dfx_B, 4gat_A |
| Binding Motifs: | pnr AthkkshGATAAgsrgvb |
| Binding Sites: | pnr_1 pnr_10 pnr_11-12 pnr_13 pnr_14 pnr_15 / pnr_16 pnr_17 pnr_18 pnr_19 pnr_2-3 pnr_20 pnr_21 pnr_22 pnr_23 pnr_24 pnr_25 pnr_26 pnr_27 pnr_28 pnr_29 pnr_30 pnr_31 pnr_4 pnr_5 pnr_6 pnr_7 pnr_8 pnr_9 |
| Publications: | Haenlin M, Cubadda Y, Blondeau F, Heitzler P, Lutz Y, Simpson P, Ramain P. Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila. Genes & development 11:3096-108 (1997). [Pubmed] |
| Related annotations: | PaperBLAST |
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