Transcription Factor
| Accessions: | FOS_MOUSE (HOCOMOCO 10), P01101 (JASPAR 2024) |
| Names: | Cellular oncogene fos, FOS_MOUSE, Proto-oncogene c-Fos, FBJ osteosarcoma oncogene, Protein c-Fos, Transcription factor AP-1 subunit c-Fos |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 380 |
| Pfam Domains: | 135-194 bZIP transcription factor 137-189 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANF 60 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 121 QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ 180 181 TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFT 240 241 LPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPDVDLSGSFYA 300 301 ADWEPLHSNSLGMGPMVTELEPLCTPVVTCTPGCTTYTSSFVFTYPEADSFPSCAAAHRK 360 361 GSSSNEPSSDSLSSPTLLAL |
| Interface Residues: | 143, 144, 147, 148, 150, 151, 154, 155, 158 |
| 3D-footprint Homologues: | 2wt7_A, 4eot_A, 7x5e_E, 7x5e_F, 6mg1_B, 1nwq_C, 1skn_P, 5vpe_C, 5vpe_D |
| Binding Motifs: | FOS_MOUSE.H10MO.A|M01093 ykcTGAyTsryy MA0099.1 rTGAsTMA |
| Publications: | Pollock R., Treisman R. A sensitive method for the determination of protein-DNA binding specificities. Nucleic Acids Res. 18:6197-6204 (1990). [Pubmed] |
| Related annotations: | PaperBLAST |
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