Transcription Factor

Accessions: 1a66_A (3D-footprint 20231221)
Names: CORE NFATC1, NF-ATc1, NFAC1_HUMAN, NFAT transcription complex cytosolic component, Nuclear factor of activated T-cells, cytoplasmic 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O95644
Length: 178
Pfam Domains: 15-175 Rel homology domain (RHD)
Sequence:
(in bold interface residues)
1 MKDWQLPSHSGPYELRIEVQPKSHHRARYETEGSRGAVKASAGGHPIVQLHGYLENEPLM 60
61 LQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDC 120
121 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS
Interface Residues: 26, 28, 29, 31, 32, 35, 125, 142, 176, 177
3D-footprint Homologues: 1p7h_L, 2o61_A, 1a66_A, 2ram_A, 1imh_C
Binding Motifs: 1a66_A GAGGAana
Binding Sites: 1a66_B
1a66_C
Publications: Zhou P., Sun L. J., Doetsch V., Wagner G., Verdine G. L. Solution structure of the core NFATC1/DNA complex.. Cell 92:687-696 (1998). [Pubmed]
Related annotations: PaperBLAST

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